http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-928714-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a0e90292f2ba83d7878baca3838b8a2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 |
| filingDate | 1962-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1963-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-928714-A |
| titleOfInvention | Process for the preparation of 4-hydroxy-3-keto-í¸-steroids |
| abstract | 4-Hydroxy-3-keto-D 4-steroid is prepared by treating a 19-nor- or a 10b -methyl-4-halo-3-keto-D 4-steroi dissolved in a t-aliphatic alcohol with oxygen in the presence of an alkali metal salt of a t-aliphatic alcohol at from 10 DEG to 50 DEG C. and, in the case of 10b -methyl reactant, catalytically hydrogenating the resulting 4-hydroxy-3-keto-D 4,6-steroid produced until one mol of hydrogen is absorbed. The above process may be modified in that the resulting 4-hydroxy-3-keto-D 4-steroid is acylated to form the corresponding 4-acyloxy compound. The initial reactants used in the above process may be a 4-chloro-D 4-steroid of the androstane, 19-nor-androstane and 17a -hydroxy-pregnane series such as 4-chlorotestosterone acetate, 4-chloro-17a -methyl-testosterone and 19-nor-testosterone, 4-chloro-19-nor-testosterone and 4-chloro-4-pregnen-17a -ol-3,20-dione. Therapeutic compositions having anabolic, androgenic and progestative activity contain as the active ingredient a 4-hydroxy (or acyloxy)-3-keto-D 4-steroid and a pharmacologically acceptable carrier. Specifications 838,773, 839,908, 848,288, 864,608, 864,610, 864,611, 864,613, 867,721, 888,665 and 922,803 also are referred to. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE39862-E http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0142275-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6710039-B1 |
| priorityDate | 1961-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.