http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-922269-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd6519950f4f9a790399c523299ed185 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-54 |
filingDate | 1959-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b619c9a06e9d7ccfc934dd6cd22a58f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_326c85575f8b4a478b175d8d2593be80 |
publicationDate | 1963-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-922269-A |
titleOfInvention | Improvements in or relating to derivatives of 1, 2, 3, 6-tetrahydro-2, 6-dioxo-4-pyrimidine-carboxylic acid |
abstract | The invention comprises compounds of the formula <FORM:0922269/IV(a)/1> in which X is one of the groups <FORM:0922269/IV(a)/2> (wherein R is hydrogen or a hydrocarbon group of at most 4 carbon atoms and R1, R2, R3 and R4 are hydrocarbon groups each containing at most 4 carbon atoms, and n is 1, 2, 3 or 4) and salts thereof; and their preparation by reacting a 6-uracil carbonyl halide with the appropriate compound HX. The halide starting material is advantageously prepared by reacting an alkali metal salt of 6-uracil carboxylic acid with oxalyl chloride, the reaction product being used as such without isolation of the pure halide. Examples are given, the products being isolated as their hydrochlorides. The uracil derivatives of the invention, which are stated to be useful in controlling the growth of micro-organisms and as cytostatics, may be formulated as pharmaceutical compositions such as tablets, pills, capsules, ampoules or other shaped products. |
priorityDate | 1959-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.