http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-918129-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9b9919d56440a76a215a8e41912e56a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G03C5-305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G03C7-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G03C5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G03C5-3035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G03C5-305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G03C5-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G03C7-30 |
| filingDate | 1959-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1963-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-918129-A |
| titleOfInvention | Pyrazolinobenzimidazole developing agents |
| abstract | The invention comprises compounds of the tautomeric formulae:- <FORM:0918129/IV (b)/1> wherein R represents hydrogen, C1-12 alkyl, aryl (optionally substituted, e.g. by amino or acylamino), aralkyl, cycloalkyl, a heterocyclic radical (e.g. a -furyl or g -pyridyl), a carbamoyl group, or a -COOR1 or -NR12 group in which R1 represents H or alkyl, and wherein the benzene ring A may be optionally substituted by one or more halogen atoms or by one or more alkoxy, aralkoxy, hydroxy, amino, carboxylic acid or sulphonic acid groups. The compounds are prepared (1) by treating pyrazolino-benzimidazoles unsubstituted in the 4-position of the pyrazoline ring with nitrous acid in an aqueous acidic solution at a temperature of from 0 to 10 DEG C., followed by reduction of the nitroso group in the resulting nitroso compound to an amino group; or (2) by coupling the aforementioned pyrazolino - benzimidazoles with diazonium salts in an alkaline or neutral aqueous solution, followed by reduction of the resulting products. 3 - Phenyl - pyrazolinobenzimidazole - 51 - sulphonic acid is prepared by heating 1-(ortho-amino - para - sulphophenyl)-3-phenyl-pyrazolone-5 with meta-toluidine. Pyrazolinobenzimidazole-3-carboxylic acid is prepared by heating 1-(ortho-aminophenyl)-carboxy-pyrazolone-5 with a mixture of aniline and aniline hydrochloride. 3 - Carboxy - pyrazolinobenzimidazole - 51 - sulphonic acid is prepared by heating 1-(21-amino-41-sulphonic acid) - phenylpyrazolone-5-carboxylic acid-3 with aniline. Pyrazolinobenzimidazole - 3,51 - dicarboxylic acid is prepared by heating 1-(21-amino-41-carboxy)-phenylpyrazolone-5-carboxylic acid-3 with a mixture of aniline and aniline hydrochloride. 3 - Methylpyrazolinobenzimidazole is prepared by heating 1-ortho-aminophenyl-3-methylpyrazolone with aniline. Pyrazolinobenzimidazole - 3 - carboxylic acid methyl ester is prepared by esterification of the corresponding acid with methanolic hydrochloric acid. Pyrazolinobenzimidazole - 3 - carbonamide is prepared by heating pyrazolinobenzimidazole-3-carboxylic acid methyl ester with aqueous ammonia under pressure. Specifications 892,886 and 918,128 are referred to. |
| priorityDate | 1958-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 38.