http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-917078-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_035d1cf7a2fed40b7fbac68b3cced081 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-96 |
| filingDate | 1960-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bb1ed6b7f804032ee4e9426bf3f3a7f |
| publicationDate | 1963-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-917078-A |
| titleOfInvention | Improvements in or relating to piperidine derivatives |
| abstract | The invention comprises compounds of the formula <FORM:0917078/IV (b)/1> (wherein Ar is a phenyl, halophenyl, methoxyphenyl or thienyl radical; Ar1 is a phenyl, halophenyl or tolyl radical; alk is an alkylene radical of 2 to 4 carbon atoms, R1 and R3 are each a hydrogen atom or an alkyl radical, R2 is a hydrogen atom or an alkyl or alkoxy radical and n is zero or 1) and their acidaddition and quaternary ammonium salts. They may be prepared from the appropriate aroyl alkyl halide Ar-CO-alk-halogen and the appropriate piperidine of the formula <FORM:0917078/IV (b)/2> itself prepared by reacting an amine of the formula <FORM:0917078/IV (b)/3> with the appropriate alkyl chloroformate, an anhydride of the appropriate acid or trichloroacetaldehyde and then debenzylating the resulting compound. Examples are given and a list of salt-forming organic and inorganic acids and quaternising agents (including ethylene chlorohydrin) is provided. The Provisional Specification describes compounds of the formula <FORM:0917078/IV (b)/4> wherein Y is phenyl, lower alkyl-phenyl, halophenyl, alkoxyphenyl or thienyl, Z is phenyl, lower alkyl-phenyl, halophenyl or alkoxyphenyl, B is lower alkylene, Alk is an alkylene chain of 1 to 4 carbon atoms, R1 is hydrogen or lower alkyl and R2 is hydrogen, lower alkyl or lower alkoxy. It also describes the preparation of gamma-chloro-4-fluoro-butyrophenone from gamma-chloro-butyryl chloride and 4-fluoro-benzene. |
| priorityDate | 1960-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.