http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-916984-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a157f5faa443ba5bb3367371f1e2a6c7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-107 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107 |
| filingDate | 1959-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1963-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-916984-A |
| titleOfInvention | Polypeptide derivatives and methods for their preparation |
| abstract | The invention comprises alkylene diamines N - monoacylated with a poly - (amino - dicarboxylic)acid, other than N - (a - poly - L - glutamyl)ethylene diamine and the preparation thereof by N-monoacylating an alkylene diamine with a poly(amino-dicarboxylic acid). The poly(amino-dicarboxylic)acids are preferably a -poly-L-glutamic, g -poly-D-glutamic, DL-anhydro-polyaspartic and a -aminoadipic acid and the alkylene diamines are ethylene diamine, putrescine, N-alkyl- and N,N-dialkyl-ethylene diamines and N-mono acetylethylene diamine. The products are preferably completely amidated i.e. substantially all the free carboxyl groups are amidated by one of the nitrogen atoms of a diamine; acylation is carried out by reacting a reactive derivative of the acid e.g. an ester or acid halide, with the diamine in an excess of at least 5 molecules of diamine per free carboxylic acid group or derivative thereof in the polypeptide chain. Mixed amides may be formed by stepwise amidation. |
| priorityDate | 1958-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.