http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-914209-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_983339daa5b5b33ca850f3dc891d60d3 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N7-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-4925 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N7-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 |
filingDate | 1960-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1962-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-914209-A |
titleOfInvention | Apparatus for analysis of blood gas |
abstract | <PICT:0914209/III/1> <PICT:0914209/III/2> A reaction chamber suitable for estimating gases contained in blood or a blood component by mixing the blood or blood component with a gas-releasing reagent, entraining the released gases in an inert gas stream and analysing the resulting gas stream by gas chromatography comprises a container divided into two compartments by a horizontal porous partition (27), having an inert gas inlet (35) in the lower compartment and a gas outlet (not visible) in the upper compartment and a passageway (38) which can be closed adapted to permit insertion of the sample and reagent into the upper compartment. As shown in Fig. 3 (to which the above numerals relate) the reaction chamber comprises a cylindrical base 21 having a recess 24 into which the inert gas is passed through line 35 and a recess 29 in which a porous polyfluoroethylene partition 27 is seated. The upper compartment is formed from an annulus 22 resting upon a sealing ring 34 in the recess 29 and a glass cap 23 similarly seated in the annulus. An annular plate 30 keeps the cap in place with the aid of screws, e.g. 31 and the annulus is screwed similarly to the base. The cap 23 is provided with an outlet (not shown) and has a serum cap-a rubber membrane 38-tied over an upper stem portion so that a sample of blood and the reagent may be introduced by means of hypodermic syringes. 39 is a bar magnet actuated by means of a rotating bar magnet 40 for stirring purposes. The upper compartment also has a valved outlet (not shown) through which reagents may be removed from the apparatus. As shown in Fig. 1 inert gas enters a thermal conductivity gas analyser 7 having thermistors 8, 8a, 9, 9a and passes through a sample inlet 10 and a four way valve 11 to the reaction chamber 12, described above. The sample inlet 10 and the valve 11 are for calibrating the apparatus by introducing a gas and passing it directly to the column 14, Inert gas and entrained gases then pass to a drying tube 13 and via valve 11 to a chromatography column 14. Where oxygen, nitrogen and carbon dioxide are to be estimated this column may be packed with silica gel which selectively retards the carbon dioxide: thermistor 9a thus provides signals corresponding to oxygen plus nitrogen and to carbon dioxide. Thereafter the gas is passed to column 15 packed with a molecular sieve and thermistor 8a provides separate signals for oxygen and nitrogen. Where only carbon dioxide is to be measured, column 15 may be omitted and the initial stream of inert gas led past thermistor 9a. For the analysis of carbon dioxide, nitrogen and oxygen in whole blood, a standard Van Slyke solution containing lactic acid, saponin, N-octyl alcohol and potassium ferrocyanide may be used; for analysis of carbon dioxide only in blood serum, dilute acid is suitable. The apparatus may be calibrated for carbon dioxide using bicarbonate in place of the blood or serum to be tested. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9823939-A1 |
priorityDate | 1959-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.