http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-911551-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42 |
| filingDate | 1960-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1962-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-911551-A |
| titleOfInvention | 1-[2-(c alkyl)-4-amino-5-pyrimidylmethyl]-(c alkyl)-pyridinium quaternary salts and compositions containing them |
| abstract | The anion, X, in quaternary salts of the general formula <FORM:0911551/IV(a)/1> may be derived from a polymer, especially it may be a polystyrenesulphonate ion; otherwise R and R1 are C1-5 alkyl groups n is 1, 2 or 3, and b and c are whole numbers such that the charge on b moles of cation is neutralized by c moles of the anion X (see also Group IV(b)).ALSO:The invention comprises pyrimidylmethylalkylpyridinium salts of the general formula <FORM:0911551/IV (b)/1> (including salts formed with polymers such as polystyrenesulphonic acid (see Group IV(a)) where R and R1 are lower alkyl radicals, n has a value 1, 2 or 3, X is an anion and b and c are positive numbers such that the positive charge of b moles of cation is neutralised by c moles of anion X, "lower" indicating 1-5 carbon atoms in the group so described; the preparation thereof by reacting a lower alkylpyridine and a 2-lower alkyl-4-amino-5-hydroxymethylpyrimidin ester of a strong acid, optionally in the form of its acid addition salt; and compositions comprising the compounds of the invention and an inert diluent. 2-Propyl-4-amino-5-bromomethyl pyrimidine dihydrobromide is prepared by reacting butyramidine with ethoxymethylene-malonitrile to give 2-propyl-4-amino-5-cyanopyrimidine, reducing this to give the 5-aminomethylpyrimidine dihydrochloride, reacting this with nitrous acid to give the -5-hydroxymethylpyrimidine and reacting this with hydrogen bromide. The 2-isopropyl-2-butyl- and 2-amyl-analogues are also prepared. Compositions for veterinary use against coccidinosis are in the form of poultry feed supplements preferably containing 1-40% of the active ingredient together with solid orally ingestible carriers, or in the form of a watersoluble powder preferably containing 1-25% of the active ingredient dispersed in an edible water-soluble carrier, or an animal feedstuff preferably containing 0.0005-0.05% of the active ingredient. |
| priorityDate | 1959-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.