http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-904123-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7780e9d205ef3d354fe484bbc65b155c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 |
| filingDate | 1959-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1962-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-904123-A |
| titleOfInvention | New cyclopentanophenanthrene compounds and process for the production thereof |
| abstract | The invention comprises 6-bromosteroids of the general formulae:- <FORM:0904123/IV (b)/1> the corresponding 3-alkyl enol ethers of the D 4 compounds, compounds of the general formula:- <FORM:0904123/IV (b)/2> (R is hydrogen or a hydrocarbon carboxylic acid acyl group of less than 12 carbons, R2 is a lower alkyl or alkinyl group of less than 6 carbons, R3 is hydrogen or methyl, X is hydrogen or fluorine and Y is a single or double bond between C1 and C2), and a process for the preparation of 6a -bromo-D 4-3-keto steroids of the androstene and pregnene series which comprises reacting the 3-alkyl ether of an appropriate D 4-3-keto steroid with hypobromous acid (or its equivalent, e.g. N-bromosuccinimide) and inverting the configuration at C6 of the resulting 6b -bromo-D 4-3-keto steroid with strong acid. The D 1,4-compounds are preferably prepared by dehydrogenation of the D 4 - compounds with selenium dioxide in t-butanol, and the corresponding 3-alkyl enol ethers are prepared by reacting the 6a - or 6b -bromo-D 4-3-ketones with a lower alkyl orthoformate. The invention is illustrated by sixteen examples. |
| priorityDate | 1958-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.