http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-899371-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J7-009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 |
| filingDate | 1959-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1962-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-899371-A |
| titleOfInvention | Steroid compounds |
| abstract | The invention comprises 17a -hydroxy-20-keto-21-diazo-steroids of the pregnane series. C21-hydrazones of 17a -hydroxy-20-keto-21-al-steroids of the pregnane series, a process for the preparation of the 21-diazo-steroids by treating the C21-hydrazones with mercuric oxide in the presence of a base such as an alkali metal or an alkaline earth metal hydroxide, a process for the preparation of C21-hydrazones by treating 17a -hydroxy-20-keto-21-al-steroids of the pregnane series with hydrazine, and a process for the preparation of 17,21-oxides of steroids by treating 21-diazo-17a -hydroxy-20-keto steroids of the pregnane series with phosphoric acid. The preferred 21-diazo-steroids have the general formula <FORM:0899371/IV (b)/1> the preferred C21- hydrazones have the general formula <FORM:0899371/IV (b)/2> and the preferred 17,21-oxides prepared by the above process have the general formula <FORM:0899371/IV (b)/3> wherein R is a keto or hydroxy group, X is a hydrogen or halogen atom, and the broken line in ring A indicates that the C1 and C2 carbon atoms may be saturated or unsaturated. 17a - Hyd oxy - 20 - keto - 21 - aldehydo steroids of the pregnane series are prepared by oxidising the correponding 21-ol steroids with copper acetate. Thus steroids of the general formula <FORM:0899371/IV (b)/4> wherein R is a keto or hydroxy group and X is hydrogen, or a halogen may be prepared. |
| priorityDate | 1958-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.