http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-893315-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bf5368888323c3ed67b85309d99a669 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_740ca626c5a63df8026edff34651cc3a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 |
filingDate | 1960-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65c85799296bdc125612982388ddf206 |
publicationDate | 1962-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-893315-A |
titleOfInvention | Steroid compounds and therapeutic compositions containing steroid compounds |
abstract | The invention comprises steroid compounds of the general formula. <FORM:0893315/IV (b)/1> wherein R represents an alkyl or cycloalkyl radical containing from 4 to 6 carbon atoms, and the preparation thereof by reacting the corresponding 3-methyl or 3-ethyl enol ether with an excess of an alcohol of the formula ROH wherein R has the above significance, in the presence of a catalytic amount of an acid catalyst, e.g. an organic sulphonic acid such as a toluene-, benzene- or naphthalene sulphonic acid. In the detailed examples the 3-butyl, sec-butyl, n-aryl, n-hexyl, 41-methylpentyl, 21-methylpentyl, 11,31-dimethylbutyl and cyclohexyl enol ethers of progesterone, the 3-cyclopentyl enol ether of 17a -hydroxy-progesterone, and the 3-n-aryl, n-hexyl, cyclopentyl and cyclohexyl enol ethers of 17a -acetoxy-progesterone are prepared.ALSO:A therapeutic composition having progestational activity and suitable for oral administration comprises one or more steroids of the general formula <FORM:0893315/VI/1> wherein R represents an alkyl or cycloalkyl radical containing from 4 to 6 carbon atoms, and a liquid or solid non-toxic pharmaceutical carrier, e.g. an orally ingestible oil or fat such as olive, sesame, linseed, sunflour, wheat germ, egg yolk or pine oil, or butter, lard, margarine or chocolate. |
priorityDate | 1960-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.