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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00
filingDate 1959-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1962-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-888974-A
titleOfInvention Steroids
abstract 2,4 - Dibromo - 16a - methyl - pregnane - 17a ,21 - diol - 3,11,20 - trione 21 - acylate is prepared by reacting 16a -methyl-pregnane-17a ,21-diol-3,11,20-trione with a brominating agent, e.g. bromine. 16a - Methyl - 1,4 - pregnadiene - 17a ,21 - diol - 3,11,20 - trione 21 - acylate is prepared by dehydrobrominating the above 2,4-dibromo compound, e.g. with a tertiary amine such as dimethylaniline or collidine, and optionally hydrolysing the 21-ester group to form the corresponding free 21-hydroxy compound. The 21-ester group may be derived from acetic, propionic, butyric or benzoic acid. Detailed examples are given. Specification 877,086 is referred to.
priorityDate 1958-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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