http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-885439-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5528d8d64c9da539b3fa8028a22bede6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 |
| filingDate | 1960-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1961-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-885439-A |
| titleOfInvention | Improvements in steroids and the synthesis thereof |
| abstract | The invention comprises cyclopentanophenanthrene compounds of the general formula <FORM:0885439/IV (b)/1> wherein R represents the acyl radical of a hydrocarbon carboxylic acid of less than 13 carbon atoms and R1 represents hydrogen or the acyl radical of a hydrocarbon carboxylic acid containing less than 13 carbon atoms, and the preparation thereof by reacting 16a ,17a -dihydroxyprogesterone with an acid anhydride or an acid halide of the required carboxylic acid to form the required 16a ,17a -diester of the above general formula, and when required, treating the diester with a dilute basic reagent such as a dilute solution of an alkali metal hydroxide or carbonate in a lower alcohol, to form the 17-monoester of the above general formula. The 17-monoester may be subsequently acylated at the 16-position to form a 16,17-diester having different ester groups. The ester groups may be derived from alkanoic, aromatic, aralkanoic, cycloalkane carboxylic, alkenoic and cycloalkene carboxylic acids. In the examples the 16, 17 - dicaproate, 17 - monocaproate, 16 - acetate 17-caproate, 16,17-diacetate, 17-monoacetate and 16-benzoate 17-acetate of 16a ,17a -dihydroxyprogesterone are prepared. |
| priorityDate | 1959-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 16.