http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-884759-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7baa0a7870a7e76138a505634dc56d50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_70d7b003d158bf22e07ce436e75f04f7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02 |
| filingDate | 1960-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1961-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-884759-A |
| titleOfInvention | Improvements in or relating to the preparation of amino acids |
| abstract | Aliphatic a -amino-carboxylic acids are prepared by reacting in an aqueous medium the corresponding a -monochlor- or a -monobromocarboxylic acid, or its ammonium salt, with hexamethylenetetramine and ammonia, the molecular ratio of hexamethylenetetramine to a -halo-acid being less than 1 : 2, and the pH of the reaction mixture being from 4 to 8. The hexamethylenetetramine may be prepared in situ from formaldehyde and ammonia. The preferred reaction temperature is 40 DEG C.-90 DEG C., and the preferred pH is 7. Examples prepare aminoacetic acid, a -alanine and valine. first reaction preferably takes place at room temperature using benzene sulphonyl chloride which is added to a suspension of the aldehyde in the tertiary base so that the temperature does not exceed 40 DEG C. The second step preferably takes place below 130 DEG C., the tertiary base then removed and the residue taken up in a neutral organic solvent for further purification. The examples describe the preparation of 4-(41-acetylamino - phenoxy) - 3 - iodo - 5 - nitrobenzaldehyde, 4 - (41 - methoxy - 31 - methyl - phenoxy) - 3 - iodo - 5 - nitrobenzaldehyde, 4 - (41 - methoxy - 31,51 - dimethyl - phenoxy) - 3 - iodo - 5 - nitrobenzaldehyde, 4 - (41 - methoxy-31,51 - di - iodo - phenoxy) - 3 - iodo - 5 - nitrobenzaldehyde, 4 - (41-methoxy-31-acetylaminophenoxy) - 3 - iodo - 5 - nitrobenzaldehyde, 4 - (41 - methoxy - phenoxy) - 3 - bromo - 5 - nitrobenzaldehyde and 4 - (41 - acetylamino - phenoxy) - 3 - bromo - 5 - nitrobenzaldehyde. Specification 843,695 is referred to. |
| priorityDate | 1959-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.