http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-882604-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 |
| filingDate | 1958-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1961-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-882604-A |
| titleOfInvention | Improvements in or relating to steroids and the manufacture thereof |
| abstract | The invention comprises a compound of the formula <FORM:0882604/IV (b)/1> wherein X is the carbonyl radical or the hydroxymethylene radical and a process for the preparation thereof which comprises subjecting a compound of the formula: <FORM:0882604/IV (b)/2> to 1 - dehydrogenation using microbiological fermentation or selenium dioxide. Suitable micro-organisms are Septomyxa, Corynebacterium and Fusarium. The 6b compound may be epimerised to the 6a compound by means of an acid or a base. Compounds produced are 1-dehydro-6a -fluoro-11b -hydroxyprogesterone, 1-dehydro-6b -fluoro-11b -hydroxyprogesterone, 1-dehydro-6a -fluoro-11a -hydroxyprogesterone, 1-dehydro-6b -fluoro-11a -hydroxyprogesterone, 1 - dehydro - 6a - fluoro - 11 - ketoprogesterone and 1-dehydro-6b -fluoro-11-ketoprogesterone. Specifications 724,094 and 874,375 are referred to.ALSO:Pharmaceutical compositions comprise a compound of the formula <FORM:0882604/VI/1> wherein X is the carbonyl radical or the hydroxymethylene radical and a pharmaceutical diluent. They are administered orally as tablets, pills, capsules, solutions, syrups and elixirs, in liquid forms for injection, or topically in the form of ointments, creams, or lotions with or without coacting antibiotics and germicides. Specifications 724,094 and 874,375 are referred to. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2487360-A1 |
| priorityDate | 1957-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID24007 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID414635703 |
Total number of triples: 15.