http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-8808839-D0
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-166 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-54 |
| filingDate | 1988-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1988-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-8808839-D0 |
| titleOfInvention | Pharmaceutical combinations |
| abstract | The use of both (i) a compound of formula (1) <IMAGE> wherein R<1> is a hydrogen atom or a methyl group; X is cis or trans -CH=CH- or -CH2CH2-, m is 2, 3 or 4 and n is 1; or X is trans -CH=CH-, m is zero and n is 3; Y is a saturated heterocyclic amino group (attached to the cyclopentane ring via the nitrogen atom) which a has 5-8 ring members and (a) optionally contains in the ring -O-, -S-, -SO2- or NR<3a>; and/or (b) is optionally substituted by one or more alkyl groups; Alk is a straight or branched C1-5 alkyl chain; l is zero or 1; p is zero, 1, 2, 3 or 4; R<2> is a hydroxyl group or a group selected from -OCOR<3>, -CO2R<3>, -CONR<3>R<4>, -SO2NR<3>R<4> -NHCOR<3>, -NHSO2R<5>, -SO2R<5>, -SR<5>, -NR<3>R<4>, -COR<5>, NHCONR<3>R<4> and -NHCSNH2; R<3>, R<3a> and R<4>, which may be the same or different, represent a hydrogen atom or a C1-4alkyl or C7-10 aralkyl group; and R<5> is a C1-4 alkyl group; or a physiologically acceptable salt, solvate or cyclodextrin complex thereof and (ii) a thrombolytic agent in the therapy or prophylaxis of thrombotic disorders. Pharmaceutical compositions containing both (i) and (ii) are also described. |
| priorityDate | 1988-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.