http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-880589-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c7d818864ce69f0dc8548437f22a997 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 1960-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1961-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-880589-A |
| titleOfInvention | New hydrazinium salts, their production and pharmaceutical compositions containing them |
| abstract | The invention comprises hydrazinium salts of the formula <FORM:0880589/IV (b)/1> (wherein "amide" represents any of the naturally occurring amido side chains present in ergot alkaloids and X is an anion bearing the charge n) and pharmaceutical compositions containing them (see Group VI). They may be prepared by reacting chloramine or hydroxylamine-O-sulphonic acid with the appropriate ergot alkaloid, such as ergot-itself or ergotamine, ergotoxine, ergonovine, methylergonovine, ergosine, ergocristine, ergocornine or ergocryptine, or isomers thereof. Anions may be exchanged by methathesis. Examples are given. Specification 858,488 and U.S.A. Specifications 2,678,258 and 2,710,248 are referred to.ALSO:Pharmaceutical compositions comprise a compound of the formula <FORM:0880589/VI/1> (wherein "amide" represents any of the naturally occurring amido side chains present in ergot alkaloids and X is an anion bearing the charge n) in admixture with a solid or liquid pharmaceutical carrier. Specified examples of X are chloride, bromide, iodide, sulphate, bisulphate, acetate, salicylate, valerate, oleate, phenate, laurate, borate, benzoate, lactate, nitrate, diglycollate, phosphate, hexafluorophosphate, phenylethylbarbiturate, o-acetoxybenzoate, citrate, dialkylbarbiturate (e.g. diethylbarbiturate), sulphothiazole, theophyllinate, urate, maleate, fumarate, succinate, tartrate, penicillinate, camphorate, salicylamide, diphenylhydantion, carbonate, cacodylate, aconitate, sulphamate, gentisate, malate and picrate. Specification 858,488 and U.S.A. Specifications 2,678,258 and 2,710,248 are referred to. |
| priorityDate | 1960-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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