http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-880071-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14effe3850d2129f863b969dac4f1db8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 |
| filingDate | 1958-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1961-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-880071-A |
| titleOfInvention | Novel í~-pregnadienes and method for their preparation |
| abstract | The invention comprises steroids of the formula <FORM:0880071/IV (b)/1> wherein R is a hydrogen atom or an alkanoyl radical containing at most 6 carbon atoms, X is -CH(OH)- or =C=O and Hal is a halogen atom) and their preparation by dehydrogenation of the corresponding 16,21-diesters saturated in the 1,2-position and, if desired, when the product is an 11-hydroxy compound oxidizing it to an 11-keto compound, and, if desired, saponifying the thus formed 16,21-diesters to the free 16,21-diols. Dehydrogenation is preferably affected with selenium dioxide, advantageously used in a solvent such as alcohol and in the presence of a lower aliphatic carboxylic acid. The oxidation may be effected with a chromium trioxide-pyridine complex. Examples describe the preparation of 9a -fluoro-steroids according to the invention. Specification 852,680 is referred to.ALSO:Pharmaceutical compositions contain, as essential active ingredient, 2-methyl- D 1,4-pregnadienes of the formula <FORM:0880071/VI/1> (wherein R is an hydrogen atom or an alkanoyl radical containing at most 6 carbon atoms, X is -CH(OH)- or =C=O and Hal is a halogen atom). They may take the form of tablets, capsules, suspensions, solutions, ointments or creams. Specification 852,680 is referred to. |
| priorityDate | 1957-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.