http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-862127-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73ee0bacab5a7576a6a3244747f6ea99 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-12 |
| filingDate | 1958-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a50fc9d7b5f63f7573c9db695f7a6c42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7256a0c22c2075b1bac871668ebbf1b |
| publicationDate | 1961-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-862127-A |
| titleOfInvention | Derivatives of 2-hydroxy-3-naphthanilide |
| abstract | The invention comprises compounds of the formula <FORM:0862127/IV (b)/1> (wherein R1 is hydrogen, an alkyl radical of at most 16 carbon atoms or a dialkylamino or aralkyl radical, R2 has the same values excluding hydrogen, or R1 and R2 are joined to form, together with the nitrogen atom, a saturated heterocyclic ring which may be alkyl substituted and wherein the benzene ring A bears at least one substituent selected from halogen atoms and alkyl of at most 6 carbon atoms, alkoxy of at most 6 carbon atoms, acyl, alkylaminosulphonyl, carboxy, benzamido, phenoxy and tolyloxy radicals provided that when this ring has a 2-methyl or 2-methoxy substituent at least one additional substituent is also present therein) and acid-addition salts thereof; and their preparation by reacting the corresponding 1 - unsubstituted - 2 - hydroxy - 3 - naphthanilide with formaldehyde or a functional derivative thereof and the amine R1R2NH. Suitably paraformaldehyde is used and the reaction is effected in a solvent such as aqueous ethanol or benzene. It may be accelerated or completed by the application of heat, by addition of excess amine or by the addition of a tertiary amine. Examples are given and hydrochlorides of some of the products are described. The Provisional Specification describes compounds of the formula <FORM:0862127/IV (b)/2> (wherein R and R1 are hydrogen or hydrocarbon radicals, optionally substituted, or form, together with the nitrogen atom, a heterocyclic ring, and the benzene ring A may optionally bear one or more substituents) other than the compounds disclosed in U.S.A. Specification 2,234,036. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7456283-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7825247-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03066613-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7816359-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9573928-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109880433-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7579467-B2 |
| priorityDate | 1958-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.