| abstract |
Analgesics of the morphine series such as morphine, codeine, codeine derivatives, dihydromorphinone, methyl-dihydromorphinone, pantopon, ethylmorphine, -ketobemidone, meperidine, dihydrocodeinone, dihydromorphine, dihydrodesoxymorphine-D, dihydrodesoxycodeine-D, dl-3-methoxy-N-methyl-morphinan and dl-3-hydroxy -N-methylmorphinan are potentiated with ibogaine or tabern-anthine. The latter are indole alkaloids isolated from the plant Tabernanthe Iboga. The weight ratio of indole alkaloid: morphine-type narcotic may be from 0,5:1 to 20:1, preferably from 2:1 to 4:1. The compositions may be prepared as tablets, capsules, pills, solutions or powders. Therapeutically active salts of the narcotic component and of the indole alkaloid component may be used e.g. hydrochloride and sulphate. |