http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-839271-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_366a19489c5e7eec53d9d57c5ca5657b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-347 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-608 |
| filingDate | 1958-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1960-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-839271-A |
| titleOfInvention | 2-(hydroxyalkyl)-bicyclo[2,2,1]-heptene and -heptane derivatives and their preparation |
| abstract | The invention comprises compounds of the general formula <FORM:0839271/IV (b)/1> (wherein R represents a straight or branched chain alkyl radical of 1-4 carbon atoms, X represents a hydrogen atom or a non-toxic salt-forming radical, and R1 represents -CH = CH-or -CH2-CH2-), and the preparation thereof by: (A) reacting 2-formyl-bicyclo-[2,2,1]-hept-5-ene with a Grignard compound R.Mg.Halogen, or (B) converting a 2-halobicyclo-[2,2,1]-hept-5-ene into its Grignard compound and reacting this with an aldehyde R-CHO, or (c) reducing a compound of the general formula <FORM:0839271/IV (b)/2> with aluminium isopropylate in isopropyl alcohol, and in each case, if desired, catalytically hydrogenating the product to convert -CH= CH- to -CH2-CH2-, or (D) reducing the starting materials of (A), (B) or (C) to the corresponding ring-saturated compounds and subjecting these to processes (A), (B) or (C); and in all cases reacting the resulting carbinols with succinic anhydride to form their succinic acid hemi-esters and, if desired, dissolving these in an aqueous solution of a salt-forming base. The products are useful therapeutically on account of the cholalogue activity. |
| priorityDate | 1957-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.