http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-830637-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_114e4423ec77cbc8dab9d0a98909704e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-105 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-105 |
| filingDate | 1958-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4204c679bfd1d6ac9e7c0380537ea1e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2fc1bfbb24b6705947061d79b0754bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d746008b855bb9d318bbbc89d59d899 |
| publicationDate | 1960-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-830637-A |
| titleOfInvention | A process for the preparation of azelaic acid semi-ester suitable for making civetone dicarboxylic acid |
| abstract | Azelaic acid semiester is prepared by oxidizing a dihydroxy-stearic acid ester to a semialdehyde ester of azelaic acid by mixing and stirring a solution of the ester in a watersoluble organic solvent, such as methyl or ethyl alcohol, with an alpha-beta glycol rupturing agent such as sodium metaperiodate, followered by distillation, and oxidizing the semialdehyde ester thus obtained to azelaic acid semiester by treating an acetone solution of the semi-aldehyde ester with an aqueous solution of potassium permanganate in the presence of an acid, such as acetic acid. The dihydroxy stearic acid ester starting material may be prepared by treatment of oleic acid or ethyl oleate with hydrogen peroxide in acetic or formic acid in the presence of sulphuric acid as a catalyst to give p 9,10-dihydroxystearic acid which is then esterified. The azelaic acid semiester prepared as above may be treated with thionyl chloride to give the acid chloride, and the latter on reaction with a tertiary amine is converted to a dimer which on saponification with alcoholic potash and subsequent acidification gives civetone dicarboxylic acid. Alternatively, the dimer is boiled with aqueous alcohol to give the ethyl ester of civetone dicarboxylic acid which is useful for the preparation of civetone and dihydrocivetone. |
| priorityDate | 1958-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.