http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-822192-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_315d611c240458b1308de8455144105a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G03C1-047 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G03C1-047 |
| filingDate | 1956-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd1a2e36a6f16f765351e95959c8c086 |
| publicationDate | 1959-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-822192-A |
| titleOfInvention | Improvements in or relating to the production of photographic emulsions |
| abstract | Polypeptides are prepared by the polymerization of pure N-carboxy-a -amino anhydrides or mixtures of such anhydrides preferably by heating the anhydrides in dioxan with sodium methylate as catalyst, or by heating above their melting points. The polypeptides may contain residues of glutamic acid together with one or more residues of lysine, sarcosine, phenylalanine, cystine, proline or glycine. Those containing lysine may be guanidated by treatment with o-methyl-isourea. In the case of amino acids such as glutamic acid and lysine, the active groups are protected during polymerization by using, as starting material g -methyl glutamate anhydride or e -carbobenzyloxy-lysine anhydride. After polymerization, the protective groups are removed by adding the polymer to hydrobromic acid in glacial acetic acid in the cold.ALSO:Polypeptides are prepared by the polymerization of pure N-carboxy-a -amino anhydrides or mixtures of such anhydrides. The polymerization is preferably effected by heating the anhydrides in dioxan with sodium methylate as catalyst, or by heating above their melting points. The polypeptides may contain residues of glutamic acid together with one or more residues of lysine, sarcosine, phenylalanine, cystine, proline or glycine. Those containng lysine may be guanidated by treatment with o-methyl-isourea. In the case of amino acids such as glutamic acid and lysine, the active groups are protected during polymerization by using, as starting material g -methyl glutamate anhydride or e - carbobenzyloxy - lysine anhydride. After polymerization, the protective groups are removed by adding the polymer to hydrobromic acid in glacial acetic acid in the cold. The N-carboxy-a -amino anhydrides are formed from the a -amino acids by treatment with benzyl chloroformate to give N-carbobenzyloxy-a -amino acids (in the case of lysine the e -NH2 group also is attacked at the same time as the a -NH2), the acid group is converted to its acid chloride and the ring closes to form the anhydride with loss of benzyl chloride. The pure anhydrides are obtained by recrystallizing several times. Specification 721,067 is referred to. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-2217817-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3907755-A |
| priorityDate | 1956-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.