http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-817329-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0b468f930dad7728c7eede92ff2e589f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4826 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4866 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 |
| filingDate | 1955-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1959-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-817329-A |
| titleOfInvention | Therapeutic compositions containing a protease |
| abstract | A dry stable therapeutic protease composition in final dosage unit form suitable for buccal administration is produced by incorporating with 0.5 to 15 mg. of protease, a pharmaceutically acceptable solid carrier therefor. The protease may be trypsin, papain, pepsin, bromelin or chymetrypsin. A pharmaceutically acceptable carrier is defined as being a water-soluble stabilizing and solubilizing agent, a dried animal substance, an encipient or a mixture thereof. Water-soluble stabilizing and solubilizing agents are solid polyethylene glycol which may have a molecular weight between 1500 and 4000, synthetic gums, e.g. methyl cellulose, alkali metal carboxymethyl celluloses such as sodium carboxymethyl cellulose, natural gums, e.g. karaya, tragacanth, agar, gum arabic, Indian gum, cherry and plum gum, carbohydrates or modified carbohydrates, e.g. sorbitol, sorbitol laurate, sorbose, sorbitan, mannitol, mannitol laurate, mannitan, dulcitol, dextrose, starch, dextrin, levulose, inositol, arabinose, beta lactose, gelatin, saccharin, sodium cyclamate, and sodium chloride. A dried animal substance is defined as a precursor enzyme, e.g. dried placent tissue, muscle tissue, amniotic fluid, human, bovine, sheep, horse and pig plasma which may be aged and subjected to ultraviolet irradiation. The excipient is defined as an inorganic or organic non-toxic compound, e.g. starch, lactose, dextrose, galactose, dextrin, magnesium oxide, hydroxide and carbonate, and aluminium hydroxide. The composition which may take the form of a tablet, or a powder contained in a capsule, e.g. a gelatin capsule, may contain in addition to or in place of the dried animal substance a ribonuclease, e.g. pancreatic desoxyribonuclease and ribonuclease. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3324002-A |
| priorityDate | 1954-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.