http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-813410-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73ee0bacab5a7576a6a3244747f6ea99 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D201-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G69-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-267 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-10 |
| filingDate | 1956-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6367091c4f7f28a8ca46b56998dd6ebf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ab7f97279700270a1f6d477178b49b4 |
| publicationDate | 1959-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-813410-A |
| titleOfInvention | Manufacture of lactams |
| abstract | Lactams are prepared from amino-esters having the formula NH2.R1.COOR2 wherein R1 is a polymethylene radical containing 3-6 carbon atoms, which may optionally bear methyl substituents, and R2 is an alkyl or cycloalkyl radical, by heating the amino-ester in the vapour phase at 250-300 DEG C. for a time insufficient for substantial polymer formation. The reaction is preferably effected in the presence of a dehydration catalyst and/or water vapour, generally at atmospheric pressure. The water vapour may be present in amounts of up to 70 per cent by weight of the amino ester. The vaporized ester may be diluted with an inert gas. In examples, isopropyl o -amino caproate or aqueous solutions of that ester or of sec.-butyl o -amino caproate are vaporized and the vapours are passed over activated alumina or Raschig rings heated to between 250 DEG and 275 DEG C. with contact times ranging from 2-7 secs., yielding caprol lactam, which is isolated by condensing the gases and fractionating the condensate. Reference is made to the use of the methyl, ethyl, isopropyl and cyclohexyl esters of o -amino-butyric, -valeric, -caproic and enanthic acids as starting materials and, as another catalyst, silica gel. Amino esters for use as starting materials may be prepared as described in Specification 810,332. |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.