http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-811957-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b6fc801b5bfe5304ffa40d938db6e09 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-44 |
| filingDate | 1957-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1959-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-811957-A |
| titleOfInvention | Improvements relating to 2-hydroxy-4-arylamino-quinolines |
| abstract | The invention comprises (1) 2-hydroxy-4-phenylamino-quinolines, the phenyl radical and fused benzene nucleus of which are each substituted by 1 to 3 halogen atoms and/or C1-6 alkyl radicals; and (2) the preparation of these and other 2-hydroxy-4-arylaminoquinolines by heating to at least 250 DEG C. (preferably 270-320 DEG C.) in the presence of aluminium chloride a malonic acid di-anilide in which the anilide groups can be substituted in any position desired except an ortho-position by substituents which do not interfere in the reaction. The products may be isolated by treating the reaction mixture with dilute acid. The examples describe the preparation of 4-anilino-2-hydroxyquinoline, 4 - para - toluidino - 2 - hydroxy - 6 - methylquinoline, 4 - (21:41 - dimethyl - anilino) 2 - hydroxy - 6:8 - dimethylquinoline, 4 - (31 - chloranilino) 2 - hydroxy - 7-chloro - quinoline and 4 - (21:51 - dichloranilino) 2 - hydroxy - 5:8 - dichloro - quinoline. The latter two compounds may be hydrolysed with hot hydrochloric acid to 7-chloro-2:4-dihydroxy - quinoline and 5:8 - dichloro - 2:4-dihydroxy-quinoline, respectively. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1601357-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006519846-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1601357-A4 |
| priorityDate | 1956-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.