http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-799343-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1a6faffc381ea8994c77336c1d3c9a0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 |
| filingDate | 1956-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1958-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-799343-A |
| titleOfInvention | Preparation of steroid compounds |
| abstract | D 1,4-3-keto-steroids are obtained by contacting a 3-keto-steroid having conjugated with said keto group one A ring double bond, with selenium dioxide at an elevated temperature in an inert organic solvent. As starting compounds there may be used cortisone, hydrocortisone, progesterone, desoxycorticosterone, corticosterone, 14-hydroxycortisone, 14-hydroxyhydrocortisone, 14 - hydroxy - 15 - bromocortisone, 14,15 - dihydroxyhydrocortisone, 9a -fluorocortisone, 9a - bromohydrocorisone, D 6-progesterone, D 14 - dehydrocortisone, D 9(11)-progesterone, 9 - hydroxyhydrocortisone and esters of those compounds having a 21-hydroxy group, e.g. the benzoates, acetates, propionates, butyrates and phthalates. As solvents there may be used ethylene glycol diethers, phenetole, xylene, dioxane and naphthalene. The addition of pyridine, dimethylaniline, diethylaniline, N - propylaniline, N - propyltoluidine, or dimethyltoluidine prevents decomposition of both the starting compounds and the produc.ts Examples disclose the preparation of D 1,4-pregnadiene - 3,20 - dione - 17a ,21 - diol acetate, D 1-dehydrocortisone acetate, D 1,4 - 9 - chloro-11,17,21 - trihydroxy - pregnadiene - 3,20-dione, D 1,4 - androstadiene - 3,17 - dione, D 1,4,7,22 ergostateraene - 3 - one, and D 1,4 - cholestadiene-3-one. |
| priorityDate | 1955-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.