http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-777517-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2fa8f8941ecc2d9521285617dbb93322 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-82 |
| filingDate | 1955-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37a34e8093bdfae4e3326ff5dad643f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2b581cbcd5cfc20b819eba532cd1750 |
| publicationDate | 1957-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-777517-A |
| titleOfInvention | Manufacture of nicotinamide |
| abstract | Nicotinamide is prepared by hydrolysing 3-cyanopyridine at elevated temperatures in an aqueous medium containing as a catalyst a compound having a solubility in water of not more than 0.1 per cent at 20 DEG C. and whose saturated aqueous solution at the same temperature has a pH value between 8 and 11, terminating the reaction when not more than 80 per cent of the 3-cyanopyridine is converted into nicotinamide and recovering nicotinamide and unreacted 3-cyanopyridine from the reaction mixture. The hydrolysis is preferably conducted at a temperature within the range 100 DEG to 130 DEG C. Specified hydrolysis catalysts are magnesium oxide, calcium carbonate and barium carbonate. The nicotinamide may be recovered by distillation and extraction of the residue with acetone. The distillate containing the unreacted 3-cyanopyridine may be passed through an ion-exchange resin to remove ammonia and the resulting solution recycled to the hydrolysis process. The nicotinamide may also be recovered by direct extraction of the aqueous reaction mixture with benzene, toluene, carbon tetrachloride, petroleum ether or chloroform. In the Provisional Specification, magnesium carbonate is also specified as a hydrolysis catalyst. Specification 563,184, [Group IV], is referred to. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114436953-A |
| priorityDate | 1955-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.