http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-773174-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-33 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-16 |
| filingDate | 1955-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1957-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-773174-A |
| titleOfInvention | Resolution of d,l-pantolactone |
| abstract | The invention comprises a compound having the formula <FORM:0773174/IV(b)/1> and a process for the resolution of a mixture of D(-)a - hydroxy - b ,b - dimethyl - g - butyro - lactone and L(+)a - hydroxy - b ,b - dimethyl - g -butyrolactone which comprises reacting the mixture with D(-) galactamine to produce the diastereoisomers (-) - N - D - dulcityl - L - (a ,g - dihydroxy-b ,b -dimethylbutyramide) and (+)-N - D - dulcityl - D - (a ,g - dihydroxy - b ,b - dimethyl-butyramide), separating the diastereoisomers from each other, e.g. by countercurrent extraction, chromatography, or fractional crystallization, and hydrolysing the separated compounds. The resulting L(+)a -hydroxy-b ,b -dimethyl-g -butyrolactone may be racemized to produce an additional quantity of D(-)a -hydroxy - b ,b - dimethyl - g - butyrolactone. The (-) pantolactone and (+) pantolactone may be reacted with D(-) galactamine by fusing together or by heating in an inert organic solvent. Examples describe the resolution of D,L-pantolactone, and the preparation of (+) dulcitylpantamide and (-) dulcitylpantamide m.p. 122-3 DEG C. and its polymorph m.p. 162-5 DEG C. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6613919-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0149671-A1 |
| priorityDate | 1954-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.