http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-772520-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b84ade043d0ba9ce6f9941e60196d24b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-14 |
| filingDate | 1955-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1957-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-772520-A |
| titleOfInvention | Improvements in or relating to the production of quinoline aldehydes |
| abstract | Quinoline aldehydes are prepared by a process wherein a methyl quinoline together with up to four times the theoretical quantity of an oxygen-containing gas (the theoretical quantity of oxygen being based on one molecule of oxygen per methyl group in the methyl quinoline) and water vapour as an inert diluent, are passed in the vapour phase at a temperature above 250 DEG C. over an oxidation catalyst comprising at least one oxide of a metal of sub-group a of the 5th, 6th or 7th groups of the periodic system in the absence of iron oxide or copper oxide. The invention also comprises an addition compound consisting of 1 mol. of quinoline-4-aldehyde, 1 mol. of lepidine and 2 mols. of water of crystallization having a melting-point of 60-62 DEG C. The reaction chamber containing the catalyst is conveniently in the form of a tube constructed of aluminium, nickel, a precious metal or a ceramic material. Nitrogen may also be used as a further diluent in the reaction mixture. The crystalline intermediate product referred to above is obtained, in the oxidation of lepidine (4-methylquinoline), from the condensed reaction mixture after it leaves the reaction zone. In examples: (1) quinaldine, air and water vapour are passed at 410 DEG C. over a 10 per cent molybdenum trioxide on silica gel catalyst, the reaction product is condensed, cooled, extracted with chloroform, the chloroform extract of aldehyde treated with sodium bisulphite solution, the quinoline-2-aldehyde being liberated from the bisulphite compound by treatment with saturated sodium carbonate solution (the quinoline-2-aldehyde may be dimerized to 2-quinaldoin by heating or by the addition of potassium cyanide solution); (2) as in (1) but oxidizing lepidine, the solid intermediate described above is obtained in the condensate, the free aldehyde being liberated therefrom by the action of sodium bisulphite solution. |
| priorityDate | 1954-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.