http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-751056-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd9f36df06271a59df790e5021907cdc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-42 |
| filingDate | 1954-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1956-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-751056-A |
| titleOfInvention | Substituted propynyl-carbinols and process for the manufacture thereof |
| abstract | The invention comprises propynyl carbinols of the general formula <FORM:0751056/IV(a)/1> wherein R is a methyl, ethyl or chlormethyl group and R1 is a chlormethyl or 2-chlorethyl group, and their manufacture by reacting a propynyl halide, preferably the bromide, with a ketone R-CO-R1 in the presence of zinc and hydrolysing the zinc compound so obtained. The reaction is preferably carried out in an inert solvent such as dry ether or ether/benzene at a temperature of about 40 DEG C., and the hydrolysis may be accomplished with dilute mineral acid, water, ammonium salt solutions or an organic acid. The primary reaction may be initiated by the addition of a trace of iodine. In examples: (1) propynyl bromide and dichloracetone give dichlormethyl-propyn-(2)-yl-carbinol; (2) propynyl bromide and chloracetone give methylchlormethyl - propyn - (2) - yl - carbinol; (3) propynyl bromide and 1-chlorobutanone-(2) give ethyl - chlormethyl - propyn - (2) - yl - carbinol; (4) Propynyl bromide and 1 - chlorbutanone - (3) give methyl - (2 - chlorethyl) - propyn - (2) - yl - carbinol. Similarly chlormethyl - (2 - chlorethyl) - propyn - (2) - yl - carbinol is obtained from 1,4 - di - chlor - butanone - (2) and ethyl-(2 - chloroethyl) - propyn - (2) - yl carbinol is obtained from 1-chlorpentanone-(3). |
| priorityDate | 1953-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.