http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-749713-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b8b744d430e252fa21c14c2b8dee176 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-12 |
| filingDate | 1953-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1956-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-749713-A |
| titleOfInvention | Improvements in or relating to the manufacture of dioxane derivatives |
| abstract | Dioxane derivatives are prepared by heating ethers of the formula <FORM:0749713/IV(a)/1> where X is halogen and R and R1 are each hydrogen or a hydrocarbon radical or together form a hydrocarbon ring, or a glycidyl ether derived from the ether by the action of alkali, with an alkali in the presence of a phenol, an amine or water. In the examples (1) (2-chloroethyl) - 2 - hydroxy - 3 - chloropropyl ether, prepared from epichlorhydrin and ethylene chlorhydrin, is boiled with aqueous NaOH and neutralized to give 2-(hydroxymethyl)-dioxane. The m-nitrobenzoate and dinitrobenzoate salts are prepared. Condensation with NaOH at 30 DEG C. or lower yields the intermediate (2-chloroethyl)-glycidyl ether; (2) 2,3-tetramethylene - 5 - hydroxymethyl - dioxane is prepared from 2 - chlorocyclohexyl - 2 - hydroxy - 3-chloropropyl ether and caustic soda; (3) 2-phenoxymethyl-dioxane is obtained by boiling (2-chloroethyl)-glycidyl ether with phenol in sodium ethoxide and then adding water and distilling off the alcohol; (4) dibutyl - (dioxane - methyl) - amine is prepared from 2-chloroethyl-glycidyl ether, dibutylamine and KOH in aqueous methanol; (5) (p-nitrophenoxy methyl) dioxane is prepared from (2-chloroethyl) - 2 - hydroxy - 3 - chloropropyl ether, p-nitrophenol and aqueous NaOH. U.S.A. Specification 2,418,297 is referred to. |
| priorityDate | 1952-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.