http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-749307-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 |
| filingDate | 1952-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1956-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-749307-A |
| titleOfInvention | Disulphide-type derivatives of vitamin b and a method of preparing same |
| abstract | The invention comprises compounds corresponding as free base to the general formula: <FORM:0749307/IV(a)/1> wherein R1 is methyl or ethyl, R2 is alkyl, e.g. CH3, C2H5, i-C3H7, n-C3H7, i-C4H2, n-C4H9, i-C5H11, n-C5H11, C8H17 and C12H25, hydroxyalkyl, e.g. -CH2CH2OH, unsaturated alkyl, e.g. CH2=CH-CH2, aralkyl, e.g. C6H5CH2, or aryl, e.g. C6H5, and R3 is hydrogen, acetyl or benzoyl, and the preparation thereof by reacting a compound of the general formula <FORM:0749307/IV(a)/2> at a non-acidic pH, with a compound containing at least one reactive group -SR2, wherein R2 is alkyl, hydroxyalkyl, unsaturated alkyl, aralkyl, or aryl, the thiazole ring being opened between 1- and 2-positions with the formation of a group -S.SR2 on the carbon atom in 5-position. As compounds containing the reactive group -SR2, there may be utilized compounds having the general formul :- <FORM:0749307/IV(a)/3> or R2-S-SO3M wherein M is an alkali metal or alkaline earth metal, or the active principle of a plant belonging to the Allium genus. The reaction may be effected in an inert solvent at a pH of at least 7 and in the presence of an oxidizing agent, e.g. bromine, hydrogen peroxide, potassium permanganate or alkali metal bichromate. |
| priorityDate | 1952-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.