http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-743677-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d037bc74e34c7d73dd883f208aef0518 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C201-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-36 |
| filingDate | 1953-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1956-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-743677-A |
| titleOfInvention | The production of an amino propanediol |
| abstract | Erythro - 1 - p - nitrophenyl - 2 - amino - 1:3-propanediols (racemic or optically active) are manufactured by selectively reducing an erythrop-p-nitrophenylserine ethyl ester with 1.05 mols. or less of lithium aluminium hydride per mol. of starting material, in an anhydrous ether medium, decomposing the resulting complex with water, filtering, treating the residue with dilute mineral acid, extracting with ethyl acetate to remove any resin, rendering the solution alkaline and then extracting the product with ethyl acetate. Examples describe the preparation of the DL, D(-) and L(+) isomers, using in the first case rather more than 1 mol. and in the other two cases rather under 0.6 mol. of LiAlH4 per mol. of ester, and working in a nitrogen atmosphere. The D(-) isomer yields chloramphenicol by epimerization according to Specification 671,531 followed by dichloracetylation according to Specification 699,575. Specifications 697,697 and 715,876 also are referred to. |
| priorityDate | 1952-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.