http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-738040-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dbb2d7ecbd600cf89fbdd230f4a466c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-74 |
| filingDate | 1953-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1955-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-738040-A |
| titleOfInvention | New arsenical compounds and processes for their preparation |
| abstract | Organo-arsenic compounds of formula <FORM:0738040/IV (b)/1> in which X is arsenoso (AsO) or arsono (AsO3H2) and R is a saturated or unsaturated alkyl group containing not more than 3 carbon atoms are obtained by reacting (a) arsenic trichloride with a tetra-substituted ethylene diamine of formula C6H5N(R)CH2CH2N(R)C6H5 or (b) ethylene dibromide with a compound of formula <FORM:0738040/IV (b)/2> (where X and R have the significance stated above). The dichlorarsine obtained by reaction (a) is converted by a base (NaOH) to the arsenone, which may be oxidized by H2O2 to form the arsonic acid. The arsenone may be obtained from the arsonic acid by reduction, e.g. with sulphur dioxide and potassium iodide. The new compounds may be used in amoebicidal compositions (see Group VI). In an example: N : N1 - dimethyl - N : N1 - diphenyl - ethylene diamine is reacted with arsenic trichloride, and caustic soda and chloroform added when reaction is complete, to precipitate the s-bis-(p-arsenoso-N-methylanilino) ethane.ALSO:Pharmaceutical compositions having amoebicidal properties comprise d -bis-(p-arsenoso- or p-arsono-N-alkylanilino) ethanes of formula <FORM:0738040/VI/1> where X is arsenoso (AsO) or arsono (AsO3H2) and R is a saturated or unsaturated alkyl group containing not more than 3 carbon atoms and a solid material or sterile parenteral liquid carrier. Such carriers include sterile water, talc, lactose, starch, stearic acid, magnesium stearate or gums. |
| priorityDate | 1953-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.