http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-737957-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J75-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J21-00 |
| filingDate | 1953-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1955-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-737957-A |
| titleOfInvention | Steroid ketals |
| abstract | The invention comprises a 3,20-cyclic diketal of a 4-chloro- or 4-bromo-pregnane-3,20-dione and the preparation thereof by mixing together an alkane-1,2-diol or an alkane-1,3-diol and a steroid 4-halo-3,20-dione having a pregnane carbon skeleton in the presence of an acid catalyst, e.g. m- and p-toluene sulphonic acids, naphthalene sulphonic acid, benzenesulphonic acid, ortho-chlorobenzenesulphonic acid, hydrochloric acid and sulphuric acid, at a temperature between about 20 DEG and 200 DEG C., to cause conversion of the 3- and 20-ketone groups to ketal groups. Examples disclose the production of 4 - chloro - 17a - hydroxypregnane - 3,11,20-trione 3,20-ethylene glycol diketal, 4-chloro-11b , 17a - dihydroxypregnane - 3,20 - dione 3,20-ethylene glycol diketal, 4-chloropregnane-3,20-dione 3,20-ethylene glycol diketal, 4-chloro-17a -hydroxypregnane-3,11,20-trione 3,20-propane-1,2 and 1,3-diol diketal, 4-bromo-17a -hydroxypregnane-3,11,20-trione 3,20-propane-1,2-diol diketal, 4 - bromo - 11b ,17a - dihydroxypregnane - 3,20 - dione - 3,20 - propane - 1,2 - diol diketal, 4 - bromopregnane - 3,11,20 - trione 3,20 - (3 - methyl - pentane - 1,2 - diol) - diketal, 4 - bromo - 12 - hydroxypregnane - 3,20 - dione 3,20 - propane - 1,3 - diol diketal and 4-chloro-11a ,17a - dihydroxypregnane - 3,20 - dione 3,20-ethylene glycol diketal. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3088945-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3079382-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-3052696-A |
| priorityDate | 1952-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.