http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-734232-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df53cdf55050f3f4580e1931741875b7 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 |
| filingDate | 1953-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1955-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-734232-A |
| titleOfInvention | Production of penicillins |
| abstract | Solid crystalline phenoxymethyl penicillin acid is prepared by growing a penicillin-producing mould in association with a culture medium and a precursor compound represented by the formula C6H5-O-CH2-R1, where C6H5-O-CH2 is the phenoxy-methyl radical and R1 represents a carboxylic acid group or functional derivative thereof such as a carboxy, carboxy-ester, carboxy salt or carboxyamide group; a carbinol; carbinyl-amine, acetal or aldehyde group, acidifying the clarified culture medium with a mineral acid to approximately pH 2.1, extracting the acidified material with a water-immiscible organic penicillin solvent, e.g. chloroform, butyl acetate or amyl acetate and recovering solid crystalline phenoxymethyl penicillin acid from the organic solvent extract. Specified precursors are phenoxyacetic acid and beta - phenoxyethanol. Phenoxymethyl penicillin acid may also be prepared by adding a mineral acid to a solution of an alkali metal salt of phenoxymethyl penicillin. Specification 643,514 is referred to. |
| priorityDate | 1952-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.