http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-731468-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc2f7134efa50484bb359fda73782848 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C335-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C335-20 |
| filingDate | 1953-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1955-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-731468-A |
| titleOfInvention | Manufacture of para-substituted diphenyl-thioureas |
| abstract | The invention comprises compounds of formula <FORM:0731468/IV (b)/1> in which one of the substituents R and R1 represents an aliphatic hydrocarbon radical (e.g. an alkyl group) containing 3 to 5 carbon atoms or an aliphatic hydrocarbon-oxygen radical (e.g. an alkoxy group) containing 2 to 5 carbon atoms, and the other represents an amino group disubstituted by two alkyl groups each containing 1 to 5 carbon atoms or by a pentamethylene group, and wherein the substituents R and R1 contain together more than 4 carbon atoms. The compounds are prepared by reacting a para-R-aniline with a para-R1-phenyl isothiocyanate or a para-R1-aniline with a para-R-phenyl isothiocyanate preferably in a neutral solvent (e.g. ethanol, benzene, toluene or propanol). Alternatively thiophosgene is reacted with a para-R-aniline and the resulting product further reacted with a para-R1-aniline. The examples describe the preparation of 1-(paradimethylaminophenyl) - 3 - (para - propyl -, isopropyl-, propoxy-, butyl-, butoxy-, isobutoxy-, isopentyl-, and isopentyloxy-phenyl)-2-thiourea, 1 - (para - diethylaminophenyl) - 3 - (paraethoxy-, butoxy-, isobutoxy-, and isopentylphenyl) - 2 - thiourea, 1 - (para - dibutylaminophenyl)- and 1-(para-piperidylphenyl)-3-(paraphenetyl)-2-thiourea. Para-substituted phenyl isothiocyanates are prepared by adding para-substituted aniline in chloroform to an aqueous suspension of thiophosgene. Para-propoxy-, butoxy-, isobutoxy-, isopentyloxy-, propyl-, isopropyl-, butyl-, and isopentylphenyl isothiocyanate are described. |
| priorityDate | 1952-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.