http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-730499-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dbb2d7ecbd600cf89fbdd230f4a466c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-52 |
| filingDate | 1952-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1955-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-730499-A |
| titleOfInvention | Improvements in or relating to pyrimidine compounds |
| abstract | The invention comprises 2-amino- and 2-acetylamino - 4 - hydroxy - 5 - (41 - chlorophenyl)-6-ethylpyrimidine, and the manufacture thereof by condensing guanidine with ethyl 2 - (41 - chlorophenyl) - 3 - oxopentanoate in a reaction medium consisting of oleum of 15-40 per cent sulphur trioxide content, and, if desired, acetylating the amino group of the product. In examples: (1) guanidine sulphate is condensed with ethyl 2-(41-chlorophenyl)-3-oxopentanoate in 20 per cent oleum; (2) guanidine carbonate is similarly condensed and the product is acetylated with acetic anhydride and pyridine. Specifications 730,472 and 730,539 are referred to. Ethyl 2 - (41 - chlorophenyl) - 3 - oxopentanoate is prepared by controlled hydrolysis of the ethyl imidoester of 2-(41-chlorophenyl)-3-oxopentanoic acid, itself obtainable from the corresponding nitrile produced by condensing ethyl propionate with 4-chlorobenzyl cyanide. |
| priorityDate | 1951-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.