http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-727635-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e28032b4dae483384b2f28cb3ee45bc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D219-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D219-14 |
| filingDate | 1953-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1955-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-727635-A |
| titleOfInvention | Therapeutically valuable acridan derivatives |
| abstract | The invention comprises quaternary salts of acridan derivatives of formula <FORM:0727635/IV (b)/1> (wherein R1 and R2 are alkyl residues which may be closed to form a ring) with arylsulphonic acid esters. The compounds are prepared by heating the acridan derivative with an arylsulphonic acid ester in a solvent such as benzene, toluene or decahydronaphthalene. In the examples N-piperidylethylacridan is reacted with methyl para-toluenesulphonate and N-diethylaminoethylacridan is reacted with methyl para-toluenesulphonate, methyl benzenesulphonate and phenyl benzenesulphonate respectively. Diethylaminoethylacridan (the hydrochloride of which is described) and N-piperidylethylacridan are prepared by reacting dihydroacridine in a toluene solution containing an alkaline substance (e.g. sodium amide, phenyllithium, finely dispersed metallic sodium or potassium, or powdered potassium hydroxide) with 1-diethylamino-2-chloroethane and b -chloroethylpiperidine respectively. |
| priorityDate | 1952-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.