http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-719295-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-43 |
filingDate | 1950-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1954-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-719295-A |
titleOfInvention | Improvements in or relating to therapeutic procaine penicillin compositions |
abstract | An aqueous injectable procaine penicillin preparation of high potency i.e. up to 1,000,000 units per e.c. which may be in the form of a dry powder for dilution with sterile water immediately prior to use, is characterized in that the procaine penicillin is (a) "micronized" i.e. has an average particle size of 5 microns (b) "milled" i.e. has average particle size of 50 microns, or (c) a mixture of the "micronized" and "milled" forms. The preparation may be fluidized by the addition of a non-toxic water-soluble penicillin salt such as the potassium, sodium, calcium and ammonium salt. The penicillin is preferably penicillin G, but other penicillins such as penicillin F and X may be used. Optional ingredients are (a) substances for rendering the suspension isotonic e.g. sodium citrate (b) dispersing agents such as polyethylene oxide derivatives e.g. polyoxyethylene sorbitan monooleate (c) preservatives e.g. methyl or propyl p-hydroxy benzoate (d) thickening agents such as sodium carboxymethyl-cellulose, natural gums e.g. tragacanth, acacia and agar agar, gelatin, polyvinyl alcohol, polyvinyl pyrrolidone and pectin. Compositions containing the procaine penicillin either in the "micronized" or "milled" form, necessarily contain the fluidizing water-soluble penicillin salt. In addition, preparations containing the "milled" form alone, preferably contain a thickening agent. |
priorityDate | 1949-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.