http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-689281-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b9eaa3e6fae959f737568474c4ae71a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 |
filingDate | 1951-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1953-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | GB-689281-A |
titleOfInvention | Improvements in or relating to the production of sulphanilamido-thiadiazoles |
abstract | The invention comprises 2-(N4-phthalylsulphanilamido) - 1,3,4 - thiadiazoles substituted in the 5-position by a lower alkyl or mononuclear aryl radical, and their preparation by reacting the correspondingly substituted 2-sulphanilamido-1,3,4-thiadiazole with phthalic acid or a functional derivative thereof. An inert solvent such as glacial acetic acid may be present during the reaction. Examples are given of the preparation of (1) 2-(N4-phthalylsulphanilamido) - 5 - methyl - 1,3,4 - thiadiazole by heating 2-sulphanilamido-5-methyl-1,3,4-thiadiazole with phthalic anhydride in the presence of glacial acetic acid; and (2) 2-(N4-phthalylsulphanilamido) - 5 - ethyl - 1,3,4 - thiadiazole; and (3) 2-(N4-phthalylsulphanilamido)-5-phenyl-1,3,4-thiadiazole by similar methods.ALSO:2-(N4-phthalylsulphanilamido)-1,3,4-thiadiazoles substituted in the 5-position by a lower alkyl or mononuclear aryl radical (see Group IV (b)), which are easily soluble at the pH value prevailing in the intestinal canal, are formed into tablets with potato starch, gelatine and talcum. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11492346-B2 |
priorityDate | 1950-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.