http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-688048-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b43a9873f4b98896475e2454c53b416 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-20 |
| filingDate | 1950-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5409a918e1546a1740ec7679b411761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70d6da9272acec4a8381e40d8e427af3 |
| publicationDate | 1953-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-688048-A |
| titleOfInvention | Production of substituted organic nitrogen bases and salts thereof |
| abstract | Substituted organic nitrogen bases or salts thereof are made by condensing a compound of formula <FORM:0688048/IV (b)/1> wherein R is an alkyl, alkenyl, aralkyl or aralkenyl group of between 8 and 20 carbon atoms, Ra is H or an alkyl or aralkyl group and R6 is H or an alkyl group, with a phosphorus halide or sulphur oxy halide and a primary, secondary or tertiary organic nitrogen base, or ammonia or a compound yielding ammonia under the conditions of the condensation, such as urea or hexamethylene tetramine, to give a salt of formula <FORM:0688048/IV (b)/2> where B is the organic nitrogen base or ammonia and X is halogen and, if desired, where B is ammonia or the initial base B contains a free H atom linked to the basic N atom, the said salt is neutralized to form the corresponding free substituted base by removal of hydrogen halide. Salts of the free base with other acids may be made by known methods The initial base may be heterocyclic, e.g. morpholine, pyridine or nicotine. In examples: (1) b -hydroxy ethyl lauramide is condensed with pyridine and phosphorus trichloride; (2) N-methyl - N - b - hydroxyethyl - oleylamide is condensed with thionyl chloride and morpholine and the free amine-amide formed and converted to quaternary salts with dimethyl or diethyl sulphate and benzyl chloride; (3) b -hydroxy-isopropylstearamide is condensed with phosphorus tribromide and diethylamine; (4) mixed ethanol-amides from palm kernel oil are condensed with dodecylamine and phosphorus trichloride and the free base of the product liberated; (5) b -hydroxy ethanolamide from palm kernel oil is condensed with phosphorus tri-iodide, prepared in situ, and pyridine; (6) b -hydroxy ethanolamide from coconut oil is condensed with diethylamine and phosphorus trichloride and the free base liberated; and (7) b -hydroxyethyl lauramide is condensed with phosphorus trichloride and urea and the free base liberated. The amide starting materials may be prepared as in Specification 631,367. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4778823-A |
| priorityDate | 1950-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.