http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-665675-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40824c489e71a02b85c9c7227fb75fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c526f3fe15af05ec67c1129d435da5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be2c0e7d5d864616741472d3169c7a58 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02 |
| filingDate | 1948-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1952-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-665675-A |
| titleOfInvention | Process for the manufacture of derivatives of hydroxy acids |
| abstract | Acylamido-salicylic acids of the formula <FORM:0665675/IV (b)/1> where R1 and R2 are hydrogen or alkyl and n is an integer are prepared by treating the halogen compounds <FORM:0665675/IV (b)/2> where X is a halogen, with ammonia or primary or secondary amines. Suitable amines are ethylamine, diethylamine, isopropylamine, butylamines, amylamines, laurylamine, stearylamine and palmitylamine; when a secondary amine is used R1 and R2 may be the same or different. The halogen compounds may be the a -chloro- or bromo-acetamido, propionamido or butyramido derivatives. The reaction is preferably carried out at low temperatures to minimise hydrolysis of the acylamido group. A solvent such as alcohol may be present, together with copper, copper-bronze, or a copper salt as catalyst. The product is conveniently isolated as a salt such as the hydrochloride. The starting materials can be prepared as in Specification 664,363. Examples show the preparation of 4-glycylamido-salicylic acid and 4-diethylaminoacetamido-salicylic acid. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2644697-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9011292-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2427327-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9011292-A3 |
| priorityDate | 1948-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.