http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-639149-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd9f36df06271a59df790e5021907cdc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 |
| filingDate | 1947-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1950-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-639149-A |
| titleOfInvention | A process for the manufacture of dl-3,4-(2-keto-imidazolido)-tetrahydrofurane-(2)-n-valeric and intermediates therefor |
| abstract | dl - 3 : 4 - (21 - Keto - imidazolido) - tetrahydrofurane-(2)-n-valeric acid of the formula <FORM:0639149/IV (b)/1> is prepared by hydrogenating the compound <FORM:0639149/IV (b)/2> in the presence of a hydrogenation catalyst, and shows vitamin activity. The starting material is obtained from 4-methyl-5-imidazolone-(2)-carboxylic acid ethyl ester which is decarboxylated to 4-methyl-imidazolone-(2) and converted into 4-methyl-5-imidazolone-(2)-e -keto-caproic acid ethyl ester as in Specification 21524/47 as open to inspection under Sect. 91(4). From this is prepared the N : N1-diacetyl-compound which is brominated in the 4-methyl group with N-brom-succinimide; the bromine atom is then replaced by an acetoxy group using silver acetate and the double bond saturated by catalytic hydrogenation. Alkaline hydrolysis of the product splits off the acetoxy group and hydrolyses the ester group to give the desired starting material. |
| priorityDate | 1945-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.