http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-638510-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a5173a7d063a9f70ca7b5e86fc23863 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C225-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C221-00 |
| filingDate | 1947-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1950-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-638510-A |
| titleOfInvention | Improvements in or relating to substituted omega-aminoacetophenones and method of preparing the same |
| abstract | Meta - hydroxy - omega - methylaminoacetophenone is prepared by continuously and separately introducing meta-benzoyloxy-omega-bromoacetophenone and methyl amine into a reaction zone containing an alkanol having from 1 to 4 carbon atoms, e.g. isopropanol, at a temperature below 65 DEG C. and removing the keto amine from the said reaction zone in a portion of the reaction medium and neutralizing the keto amine containing the product substantially as rapidly as it is formed. Preferably an excess of the amine is employed and a reaction temperature of 45-65 DEG C. is maintained. In an example, m-benzoyloxy-o -bromoacetophenone in isopropanol and aqueous methylamine are gradually added to a reaction vessel and the reacted product is continuously run off into an excess of hydrochloric acid from which m-hydroxy-o -methylaminoacetophenone hydrochloride is isolated. |
| priorityDate | 1945-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.