http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-608208-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2dbb2d7ecbd600cf89fbdd230f4a466c |
| filingDate | 1946-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1948-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-608208-A |
| titleOfInvention | Process for the preparation of phenthiazine derivatives |
| abstract | Amino derivatives of phenthiazine of the formula <FORM:0608208/IV(b)/1> (in which R1 and R2 are H or alkyl groups, R3 and R4 are alkyl groups, and n is an integer greater than 1) are made by reacting phenthiazine, or a phenthiazine in which the benzene nuclei contain alkyl or alkoxy groups, with a dialkylaminoalkyl halide in the presence of an acid-binding agent, e.g. sodamide. In examples: (1) N-diethylaminoethylphenthiazine is obtained by heating phenthiazine, xylene and sodamide under reflux and diethylaminochloroethane; N - diethylaminopropyl - phenthiazine and N - dimethylaminoethyl-phenthiazine are prepared similarly; (2) N - (31 - dimethylaminopropyl) - phenthiazine is similarly prepared from phenthiazine and 3-dimethylamino-1-chloropropane; (3) N-(21-dimethylamino-21-methylethyl)-phenthiazine is made similarly using 1-dimethylamino - 2 - chloropropane; (4) N - (21-dimethylaminoethyl) - 2 - methoxyphenthiazine is made by heating 2-methoxyphenthiazine, xylene, sodamide and dimethylamino-chloroethane; (5) N-(21-dimethylamino-21-methylethyl) -2-methoxyphenthiazine is made similarly from 2-methoxyphenthiazine and 1-dimethylamino-2-chloropropane; (6) N-(31-dimethylamino-21,21-dimethylpropyl) -phenthiazine is made similarly from phenthiazine and 1-dimethylamino-2,2-dimethyl-3-chloropropane. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-1034638-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2692266-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-1034639-B |
| priorityDate | 1945-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.