http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-593522-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_571b8abacacea64d3f7089d0983b8b3b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3a96f191aa088181271e2dfe1531ebd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-06 |
| filingDate | 1945-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1947-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-593522-A |
| titleOfInvention | Improvements in and relating to the preparation of thiazolidine derivatives |
| abstract | N-Formylthiazolidine carboxylic acid amides are manufactured from the corresponding acids, of the general formula <FORM:0593522/IV/1> (wherein R1 and R4 represent hydrogen or alkyl radicals and R2 and R3 represent alkyl radicals) by treating them in an inert solvent with a slight excess over one molecular proportion of thionyl chloride, and treating the resulting acid chloride (which need not be purified) with excess of ammonia. Suitable starting materials are the products obtained by the action of formic acid and acetic anhydride on the corresponding thiazolidinecarboxylic acids prepared as described in Specification 584,918. In an example, N - formylisopro - pylidenepenicillamine (R1 = R2 = R3 = R4 = CH3) is heated with thionyl chloride in dry benzene, the solution is evaporated in vacuo and the residue is treated with .880 ammonia in the cold. Specification 585,413 also is referred to. According to the Provisional Specification, R1, R2, R3 and R4 in the general formula above may each represent hydrogen or an alkyl, aryl or aralkyl radical, and the substituent in the 3-position is formulated as -COR5, where R5 likewise represents hydrogen or an alkyl, aryl or aralkyl radical. |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.