http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-536216-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_867f5c494a68e47c58c46e78a144c4e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_657c161ccc2002fbf2ae3d4c68ae9e6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eda6ffec064a97d159240d081cf48caa |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-69 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-69 |
| filingDate | 1939-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1941-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-536216-A |
| titleOfInvention | Improvements in or relating to the manufacture of amino cyclic sulphonamides and their derivatives |
| abstract | 536,216. Sulphonamido compounds. WARD, BLENKINSOP & CO., Ltd., WIESNER, B. P. H., and KATSCHER, E. Sept. 1, 1939, Nos. 25149 and 33054. [Class 2 (iii)] p - - Aminobenzenesulphonamido - pyridines, - quinolines, -isoquinolines and -thiazoles are prepared by interaction of p-aminobenzenesulphofluoride with primary or secondary amines of the pyridine, quinoline, isoquinoline or thiazole series. Tertiary amines such as dimethylaniline may be present as acid acceptors. The products include those formed by condensation of further quantities of the sulphofluoride with the first reaction product, and are useful therapeutically. Examples are given of the preparation of the p-aminobenzenesulphonyl derivatives of 2-aminopyridine and of 2-amino- 4-methylthiazole. In the case of the treatment of 2-aminopyridine, the product consists of both 2 - (p - aminobenzenesulphonyl) - aminopyridine and its p-aminobenzenesulphonyl derivative formed by substitution of the free amino group. Specifications 512,145, 517,272, 531,167 and 533,495 are referred to. The Provisional Specifications also describe the treatment of heterocyclic amino compounds or their alkali metal compounds with amino-cyclic-sulphofluorides whose amino group has been protected, the protective group being subsequently split off, and contain an additional example of the interaction of p-acetylaminobenzenesulphofluoride with α-aminopyridine and the hydrolysis of the product. Anhydrous metal halides may be present as catalysts. p- Aminobenzenesulphofluoride is obtained by reacting fluorsulphonic acid with p-aminobenzenesulphonic. acid. |
| priorityDate | 1939-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.