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filingDate 1939-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1941-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber GB-533354-A
titleOfInvention Process for the manufacture of new organic antimony compounds
abstract 533,354. Organic antimonycompounds. SOC. DES USINES CHIMIQUES RHONEPOULENC., and GAILLIOT, P. L. May 11, 1939, No. 14087. [Class 2 (iii)] Organic antimony compounds of therapeutic value are prepared by neutralizing antimonic acid with an aliphatic polyhydroxyamine in which at least two hydroxyl groups are attached to the same carbon chain. The antimonic acid may be formed during the reaction, e.g., from antimony pentachloride. The compounds may also be prepared by reacting known amineantimoniates with a salt of the polyhydroxyamine whereby the amine component is replaced by the polyhydroxyamine, or by carrying out the foregoing processes with a derivative of trivalent antimony and oxidizing the product. The antimony compounds give stable solutions in the presence of sodium chloride. According to the examples : (1) A solution of antimony pentachloride in chloroform is added to a solution of N-methylglucamine in aqueous diethylamine; the chloroform is decanted and the aqueous solution poured into alcohol to precipitate the antimoniate of methylglucamine; (2) the same product is obtained by interaction of calcium antimoniate with N-methylglucamine oxalate ; or (3) by replacing the antimony pentachloride in the process of (1) by the trichloride and oxidizing the product in solution with hydrogen peroxide; (4) galactamine and glucamine antimoniates are formed when the process of (1) is carried out with the use of galactamine or glucamine in place of N-methylglucamine ; (5) the antimoniate of aminopropanediol is prepared by neutralizing antimonic acid with the amino-alcohol.
priorityDate 1939-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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