http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-515501-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6108de85602f2fc901e5daf4c38fa166 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-16 |
| filingDate | 1938-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1939-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | GB-515501-A |
| titleOfInvention | Process for the production of alkamine esters |
| abstract | 515,501. Alkamine esters. CHEMISCHE FABRIKEN J. WIERNIK & CO. AKT.-GES. June 3, 1938, No. 16750. Convention date, June 5, 1937. [Class 2 (iii)] Alkamine esters having therapeutic properties are prepared from halogen hydracid esters of the alkamines by converting the latter esters into salts of the acids by reacting together stoichiometrical amounts of the said esters and acids or by double decomposition between salts of the acid and halogenhydracid ester, and heating the salts of the acids so prepared in the absence of face acid or alkali to above 50‹C. until transposition of the halogen and acid .radicle takes place. In examples : (1) trimethylbromethyl ammoniumbromide is reacted with the following salts and then converted into the corresponding esters by heating: silver lactate, silver acetate, silver mandelate, silver thiocyanate, silver phenylquinoline carboxylate, silver desoxycholate and silver cholate ; (2) diethylchlorethylamine is converted into salts by addition of p-nitrobenzoic acid, thiocyanicacid, benzilic acid, diphenylacetic acid, salicylic acid, mandelic acid and trichlorbutyladipic acid and the resulting' salts converted into the desired esters by heating ; (3) diethylchlorethylamine hydrochloride is reacted with silver theobromine 1-acetate, the silver chloride removed and the product heated on the water-bath ; (4) #-piperidinoethylchloride is reacted with benzoic acid and the product heated to give the hydrochloride of #- piperidinoethyl benzoate ; (5) diethylchlorpropylamine is reacted with cinnamic acid in alcoholic solution, the alcohol removed from the product and the residue heated to convert it into the hydrochloride of diethylaminopropylcinnamate. The Specification as open to inspection under Sect. 91 comprises also examples in which the following pairs of components are reacted together: trimethylbromethylammoniumbromide and silver pyroracemate or mandelate, 2:2-dimethyl -3-diethylaminopropyl-1-chloride and tropic acid, diethylchlorethylamine and monobenzylphthalic acid, diethylaminoethylchloridehydrochloride and sodium benzilate. - This subject-matter does not appear in the Specification as accepted. |
| priorityDate | 1937-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.